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Alfa Aesar™ Lovastatin, 97%

Manufacturer:  Alfa Aesar™ H5279206

Quantity 5g

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Catalog No. AAH5279206


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Specifications

Description

Applications
Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

Solubility
Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Description & Specifications

Chemical Identifiers

75330-75-5
404.56
Mevacor
C24H36O5
MFCD00072164
Lovastatin

Specifications

75330-75-5
404.56
Mevacor
5g
97%
C24H36O5
MFCD00072164
175°C
Lovastatin

Safety and Handling

SDS & Safety Documents

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : EK7907000

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