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Lovastatin, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Indirectly inhibits Rho-GTPase activity by depleting intracellular pool of isoprene residues. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Inactive lactam prodrug of lovastatin hydroxy acid, naturally bioactivated in vivo following oral administration.
Specifications
Quantity | 50 mg |
Formula Weight | 404.54 |
Percent Purity | >98% |
Chemical Name or Material | Lovastatin |
Safety and Handling
Recommended Storage | Store at Room Temperature |
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