LOX Mouse anti-Human, Clone: OTI9G6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525033
DescriptionLysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Protein-lysine 6-oxidase antibody, EC 188.8.131.52 antibody, Lysyl oxidase antibody.|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 22-168 of LOX produced in HEK293T cell|
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