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LOXL2 Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 702694

Encompass

Catalog No. 70-269-4


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Description

Description

This antibody is predicted to react with Monkey, Bovine, Cat Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.
Specifications

Specifications

LOXL2
Recombinant Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
Q9Y4K0
LOR2, WS9-14, lysyl oxidase homolog 2, lysyl oxidase related 2, lysyl oxidase-like protein 2, lysyl oxidase-related protein 2, lysyl oxidase-related protein WS9-14
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4017
Immunocytochemistry, Immunofluorescence, Western Blot
7H25L21
Unconjugated
LOXL2
Liquid
LOXL2
Peptides corresponding to human LOXL2 [1) aa28-aa45 2) aa239-aa258]
Protein A
RUO
Antibody
Monoclonal
Human
SDS
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