LOXL2 Mouse anti-Human, Clone: OTI8G5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526874
DescriptionLysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|LOR2, WS9-14, lysyl oxidase homolog 2, lysyl oxidase related 2, lysyl oxidase-like protein 2, lysyl oxidase-related protein 2, lysyl oxidase-related protein WS9-14|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit protein fragment corresponding to amino acids 152-450 of LOXL2 produced in E.coli|
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