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LPAM-1 Rat anti-Mouse, PE, Clone: DATK32, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MLPAM104

Catalog No. 50-113-7527


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Description

Description

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

LPAM-1
Monoclonal
0.1 mg/mL
PBS with 0.1% sodium azide
P26011, Q00651
ITGB7, Gut homing receptor beta subunit, Integrin alpha-4/beta-7, Peyer patches-specific homing receptor LPAM-1, Itga4
Rat
IgG2a, kappa
100 μg
4° C
Primary
16401, 16421
Flow Cytometry
DATK32
PE
Itga4
Liquid
Itga4, Itgb7
Mouse LPAM-1.
Purified
RUO
Antibody
Monoclonal
Mouse
Documents
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