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LRRC15 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550442

Catalog No. PA550442


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Description

Description

The antibody detects endogenous levels of total LRRC15 protein.

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer ft.s disease.
Specifications

Specifications

LRRC15
Polyclonal
Unconjugated
LRRC15
Liquid
LRRC15
Fusion protein corresponding to a region derived from internal residues of human leucine rich repeat containing 15
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
2.7 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q8TF66
LIB
Rabbit
IgG
100 μL
-20°C
Primary
131578
Documents
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