Invitrogen™ LRRC25 Monoclonal Antibody (OTI3E4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526015

Catalog No. PIMA526015

Description

LRRC25 Monoclonal Antibody for Western Blot, Flow

Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA. [UniProt].

Specifications

• Antigen: LRRC25
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8N386
• Gene Symbols: LRRC25
• Immunogen: Full length human recombinant protein of LRRC25 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI3E4
• Conjugate: Unconjugated
• Gene: LRRC25
• Gene Alias: leucine rich repeat containing 25; leucine-rich repeat-containing protein 25; LRRC25; MAPA; monocyte and plasmacytoid activated molecule; monocyte and plasmacytoid-activated protein; UNQ6169/PRO20174
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126364
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid