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LRRK2 [D1994A] Human Protein

$438.00


Products 1
Catalog Number Mfr. No. Description Price Qty Availability  
Catalog Number Mfr. No. Description Price Qty Availability  
PV6051 Non-distribution product as customer accommodation.
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LIFE TECHNOLOGIES
PV6051
N/A 10μg
Each for $438.00
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Description

Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates.
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Safety and Handling

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