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BioVision IncSupplier Diversity Partner LRRK2 (Human) ELISA Kit: A sandwich ELISA kit for the quantitative measurement of LRRK2 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids. DFS Item

Manufacturer:  BioVision IncSupplier Diversity Partner K4228100

LRRK2 (Human) ELISA Kit; Leucine-rich repeat serine/threonine-protein kinase 2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, & calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes & the Golgi aPPARγ tus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease. BioVision's LRRK2 ELISA kit is a s&wich ELISA assay for the quantitative measurement of human LRRK2 in serum, plasma & cell culture supernatants.

Catalog No. 50-113-2431

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