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Invitrogen™ LRRK2 WT Full Length Protein Non-distribution product as customer accommodation.

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.

Manufacturer:  Invitrogen™ A15197

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Catalog No. A15197


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Description

Description

This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying Parkinson's disease.

  • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
  • Uncover novel compounds or hits specific to the full-length form
  • Advance Parkinson's research using the full-length protein and validated assays
Specifications

Specifications

NP_940980.3
120892
10μg
RUO - research use only
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Baculovirus
Human
Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis
288kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.
Full Length
Kinase Assay
LRRK Kinase Family
DYKDDDDK
Documents
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