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LRRTM2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 230941AP

Catalog No. 50-173-3996


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Description

Description

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.
Specifications

Specifications

LRRTM2
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43300, Q8BGA3
KIAA0416, LRRN2, LRRTM2
Rabbit
IgG
150 μL
-20°C
Primary
107065, 26045
Western Blot
Unconjugated
LRRTM2
Liquid
LRRTM2
LRRTM2 Fusion Protein Ag19422
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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