Tocris™ Lu AA 47070

Prodrug of a potent and selective adenosine A2A receptor antagonist

Manufacturer: Tocris™ 4783/50

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Catalog No. 47-835-0

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For Research Use Only


    Inhibitors Lu AA 47070
    Purity >98
    Quantity 50mg
    Product Type Lu AA 47070
    Molecular Weight 463.39

    Prodrug of a potent and selective adenosine A2A receptor antagonist (Ki values are 5.9, 260, 410 and <10,000nM for A2A, A2B, A1 and A3 receptors respectively. Reverses parkinsonian motor impairment and motivational effects produced by dopamine D2 receptor blockade in rats. Orally bioavailable.

    • Chemical Name: 4-[(3,3-Dimethyl-1-oxobutyl)amino]-3,5-difluoro-N-[3-[(phosphonooxy)methyl]-2(3H)-thiazolylidene]benzamide
    • Formula: C17H20F2N3O6PS
    • CAS Number: 913842-25-8
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

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