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Tocris™ LU AA33810

Potent NPY Y5 receptor antagonist

Manufacturer:  Tocris™ 3562/10

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Catalog No. 35-621-0R

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For Research Use Only



Potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5nM in vitro). Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478nM respectively). Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.
  • Chemical Name: N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]methanesulfonamide
  • Formula: C19H25N3O2S3
  • CAS Number: 304008-29-5
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >98
Description & Specifications


LU AA33810
LU AA33810
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