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Ly-108 Mouse anti-Mouse, Clone: eBio13G3-19D (13G3-19D), eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$97.00 - $271.00

Specifications

Antigen Ly-108
Clone eBio13G3-19D (13G3-19D)
Target Species Mouse
Conjugate Unconjugated
Isotype IgG2a, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-129-06 Non-distribution product as customer accommodation.
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Invitrogen
14150880
25 μg
Each for $97.00
Add to cart
 
50-129-07 Non-distribution product as customer accommodation.
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Invitrogen
14150882
100 μg
Each for $271.00
Add to cart
 
Description

Description

Description: The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions. Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested. Applications Reported: This eBio13G3-19D (13G3-19D) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunoblotting (WB). Applications Tested: This eBio13G3-19D (13G3-19D) antibody has been tested by flow cytometric analysis of mouse splenocytes and thymocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
Specifications

Specifications

Ly-108
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C
eBio13G3-19D (13G3-19D)
Unconjugated
Flow Cytometry, Immunoprecipitation, Western Blot
Primary
Monoclonal
TBS with 0.09% sodium azide; pH 8.0
RUO
SDS

For Research Use Only.

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