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  6. LY 379268, Tocris Bioscience™ 

LY 379268, Tocris Bioscience™

Catalog Number 245350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
191471-52-0
C7H9NO5
187.151
YASVRZWVUGJELU-MDASVERJSA-N
1r,4r,5s,6r-4-amino-2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, d07grg, 4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1r,4r,5s,6r-4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1s,2r,5r,6r-2-amino-4-oxabicyclo 3.1.0 hexane-2,6-dicarboxylic acid, 2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 4-amino-, 1r,4r,5s,6r-rel
10197984
(1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
C1C(C2C(C2O1)C(=O)O)(C(=O)O)N
This item is not returnable. View return policy
191471-52-0
C7H9NO5
187.151
YASVRZWVUGJELU-MDASVERJSA-N
1r,4r,5s,6r-4-amino-2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, d07grg, 4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1r,4r,5s,6r-4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1s,2r,5r,6r-2-amino-4-oxabicyclo 3.1.0 hexane-2,6-dicarboxylic acid, 2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 4-amino-, 1r,4r,5s,6r-rel
10197984
(1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
C1C(C2C(C2O1)C(=O)O)(C(=O)O)N

Description

Highly selective group II mGlu agonist

LY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active. LY379268 disodium salt also available.
Quantity 50 mg
Formula Weight 187.15
Percent Purity >99%
Chemical Name or Material LY 379268

Safety and Handling

Recommended Storage Store at +4°C
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