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Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor™ 450, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$128.00
Specifications
Antigen | Ly-6G |
---|---|
Clone | 1A8-Ly6g |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
48-966-880
|
Invitrogen
48966880 |
25 μg |
Each for $128.00
|
|
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48-966-882
|
Invitrogen
48966882 |
100 μg |
Each for $128.00
|
|
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Description
Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25-kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown. Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity. Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 450 is an alternative to Pacific Blue™. eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.
Ly-6G Monoclonal antibody specifically detects Ly-6G in Mouse samples. It is validated for Flow Cytometry.Specifications
Ly-6G | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G | |
Ly6g | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Ly6g |
1A8-Ly6g | |
Flow Cytometry | |
eFluor 450 | |
Rat | |
Mouse | |
P35461 | |
546644 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.
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