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Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor™ 450, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

$128.00

Specifications

Antigen Ly-6G
Clone 1A8-Ly6g
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
48-966-880
Encompass_Preferred
View Documents
Invitrogen
48966880
25 μg
Each for $128.00
Add to Cart
 
48-966-882
Encompass_Preferred
View Documents
Invitrogen
48966882
100 μg
Each for $128.00
Add to Cart
 
Description

Description

Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25-kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown. Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity. Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 450 is an alternative to Pacific Blue™. eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.

Ly-6G Monoclonal antibody specifically detects Ly-6G in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

Ly-6G
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Ly6g
Primary
4° C, store in dark, DO NOT FREEZE!
Ly6g
1A8-Ly6g
Flow Cytometry
eFluor 450
Rat
Mouse
P35461
546644
IgG2a κ
Affinity chromatography
Antibody
SDS
Documents

Documents

Product Certifications

For Research Use Only.

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