LYK5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141207

Catalog No. 01-675-767

Description

LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524. Gene Map Locus is 17q23.3 and members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.

Specifications

• Antigen: LYK5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STRADA
• Gene Alias: 2610019A05Rik; 6030402H20Rik; AI480680; E130112C09Rik; LYK5; NY-BR-96; PMSE; protein kinase LYK5; serologically defined breast cancer antigen NY-BR-96; STE20-like pseudokinase; STE20-related adapter protein; STE20-related kinase adapter protein alpha; STE20-related kinase adaptor alpha; Stlk; Strad; STRAD alpha; Strada
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 72149, 92335
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: Q3UUJ4, Q7RTN6
• Gene Symbols: STRADA
• Immunogen: Synthetic peptide corresponding to residues 300-350 of human STRAD (isoform 1).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG