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Lymphotoxin beta Receptor Rat anti-Mouse, Biotin, Clone: eBio3C8 (3C8), eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$119.00 - $303.00

Specifications

Antigen Lymphotoxin beta Receptor
Clone eBio3C8 (3C8)
Target Species Mouse
Conjugate Biotin
Isotype IgG1, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-118-99 Non-distribution product as customer accommodation.
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Invitrogen
13567180
25 μg Each for $119.00
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50-119-00 Non-distribution product as customer accommodation.
View Documents
Invitrogen
13567182
100 μg Each for $303.00
Add to cart
 
Description

Description

Description: The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxin-alpha and lymphotoxin-beta. This LT-alpha/LT-beta heterotrimer (LT-alpha1beta2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120alpha) or TNFR2 (CD120beta). LTBR is expressed by day 7 embryos, so it has been speculated that the LT-alpha/LT-beta receptor system may also have some function in early embryogenesis. Applications Reported: This eBio3C8 (3C8) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio3C8 (3C8) antibody has been tested by flow cytometric analysis of NIH/3T3 cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended to block Fc gamma-receptors with anti-mouse CD16/32 (cat. 14-0161), prior to staining to prevent non-specific binding of eBio3C8.

Furthermore, it is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 µm post-manufacturing filtered. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
Specifications

Specifications

Lymphotoxin beta Receptor
Mouse
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
eBio3C8 (3C8)
Biotin
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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