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M 25, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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C23H29N3O2
This item is not returnable. View return policy
C23H29N3O2

Potent Smoothened (Smo) receptor antagonist

Potent Smoothened (Smo) receptor antagonist (IC50 = 5 nM). Inhibits the Hedgehog signaling pathway. Inhibits Shh induced Gli luciferase reporter activity in Shh-light 2 cells (IC50 = 5 nM). Antagonizes GSA-10 and SAG -mediated differentiation of the C3H10T1/2 cell line (IC50 values are 69 and 115 nM, respectively).

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Quantity 10mg
Color Orange
Formula Weight 379.5
Physical Form Solid
Percent Purity >98%
Chemical Name or Material M 25

Recommended Storage : Store at +4°C