Thermo Scientific™ MAbPac™ SCX-10 LC Columns

Use these strong cation-exchange columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants.

Manufacturer: Thermo Scientific™ 082674

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Catalog No. 03-251-004

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    Column Type Ion Exchange
    Type Analytical Column
    Carbon Load -
    USP Type N/A
    Endcapped -
    Max. Pressure 7000psi
    Packing Material Spherical, non-porous polymer
    Particle Size 5µm
    Temperature 60°C
    Pore Size Non-porous
    pH 2 to 12
    Stationary Phase Sulfonate
    Surface Area -
    Length (Metric) 50mm
    Column Format Analytical Column
    Diameter (Metric) 4.6mm

    Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

    Superior Performance for mAb Variant Analysis

    • Exceptionally high resolution for mAb variants
    • Ideal for characterization and quality control assessment of mAbs
    • Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
    •  Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
    • Meets the regulatory requirements for biopharmaceutical characterization
    Multiple Sizes Available
    • Available in 3, 5 and 10µm particle sizes in standard and UHPLC formats
    • Smaller-particle-size columns provide the same resolution as the 10µm columns, but with significantly faster analysis time

  • Description & Specifications

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