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Thermo Scientific™ Lab Vision™ MAGE-1 Ab-4, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Specifications

Antigen MAGE-1 Ab-4
Clone MA454
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Host Species Murine
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Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS1067R1
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Thermo Scientific™
MS1067R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy

Host Species: Mouse

Clone: MA454

Isotype: IgG1/κ

Species Reactivity: Human, Dog and Rat. Others not known.

Immunogen: Partially purified, full-length recombinant human MAGE-1 protein

Molecular Weight: 42-46kDa

Positive Control: Colo32 cells germ cells in testis

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

MAGE-1 Ab-4
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Murine
Cancer and Tumor Biology
Partially purified, full length recombinant human MAGE-1 protein
MA454
Monoclonal
RUO
Primary
IgG2a, κ
SDS
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