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MAGE 1 Mouse anti-Human, Rat, Canine, Alexa Fluor™ 350, Clone: MA454, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233094AF350

Catalog No. NP233094A30



Description

Description

MAGE 1 Monoclonal antibody specifically detects MAGE 1 in Human,Rat,Canine samples. It is validated for ELISA.
Specifications

Specifications

MAGE 1
MA454
ELISA
Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326
Mouse
IgG1 Kappa
Store at 4°C in the dark.
Monoclonal
Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients′ autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
ELISA
Alexa Fluor™ 350
50 mM sodium borate with 0.05% sodium azide
MAGEA1
Human MAGE-A1 full length recombinant protein
0.1 mL
Primary
4100
Canine, Human, Rat
Documents
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