Invitrogen™ MAGED1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588059

Catalog No. PIPA588059

Description

Immunogen sequence: EAVLWEALRK MGLRPGVRHP LLGDLRKLLT YEFVKQKYLD YRRVPNSNPP EYEFLWGLRS YHETSKMKVL RFIAEVQKRD PRDWTAQFME AADEALDALD AAAAEAEARA EARTRMGIGD EAVSGPWSWD DIEFELLTWD EEGDFGDPWS RIPFTFWARY HQNARSRFPQ TFAGPIIGPG GTASANFAAN FGAIGFFWVE; Positive Samples: Mouse liver, Mouse lung, Rat lung, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein.

This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: MAGED1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGED1
• Gene Alias: 11B6; 2810433C11Rik; 5430405L04Rik; BCG-1; Dlixin; Dlxin1; DLXIN-1; DXBwg1492e; JCL-1; MAGE family member D1; MAGE tumor antigen CCF; MAGED1; MAGE-D1; MAGE-D1 antigen; Maged2; melanoma antigen family D, 1; melanoma antigen family D1; melanoma antigen, family D, 1; melanoma-associated antigen D1; mFLJ00163; neurotrophin receptor-interacting MAGE homolog; NRAGE; PP2250; PRO2292; Sertoli cell necdin-related gene protein 1; SNERG-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84469, 94275, 9500
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9ES73, Q9QYH6, Q9Y5V3
• Gene Symbols: MAGED1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 635-834 of human MAGED1/NRAGE (NP_0010053331).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov