MAGI3 Polyclonal Antibody, Invitrogen™

Sheep Polyclonal Antibody

Supplier:  Thermo Scientific PA112323

Catalog No. 01-674-107

Description

Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is them followed by 5 PDZ domains.

Specifications

• Antigen: MAGI3
• Classification: Polyclonal
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: Q5TCQ9
• Gene Symbols: MAGI3
• Immunogen: Recombinant protein corresponding to PDZ domain 4-5 of MAGI-3.
• Quantity: 250 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: MAGI3
• Gene Alias: 4732496O19Rik; 6530407C02Rik; AA407180; AI120132; dJ730K3.2; GKWW domain; KIAA1634; Magi3; MAGI-3; membrane associated guanylate kinase, WW and PDZ domain containing 3; membrane-associated guanylate kinase inverted 3; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; membrane-associated guanylate kinase-related (MAGI-3); membrane-associated guanylate kinase-related 3; mKIAA1634; PDZ 4-5; RP4-730K3.1; scaffolding protein SLIPR; scaffolding-like protein; Slipr
• Host Species: Sheep
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 260425
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid