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MALT1 Mouse anti-Human, Alexa Fluor™ 594, Clone: MT1/410, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233054AF594

Catalog No. NP23304A94


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Description

Description

MALT1 Monoclonal antibody specifically detects MALT1 in Human samples. It is validated for ELISA.
Specifications

Specifications

MALT1
MT1/410
ELISA
Conjugated, Purified
MALT1
Human MALT1 recombinant fragment (aa701-808)
Protein G purified
Apoptosis, Cancer, Tumor Suppressors
Primary
10892.0
Human
ELISA
Alexa Fluor™ 594
50 mM sodium borate with 0.05% sodium azide
caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
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