MALT1 Mouse anti-Human, Alexa Fluor 750, Clone: MT1/410, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233054AF750
DescriptionMALT1 Monoclonal antibody specifically detects MALT1 in Human samples. It is validated for ELISA.
|Human MALT1 recombinant fragment (aa701-808)|
|Protein G purified|
|Apoptosis, Cancer, Tumor Suppressors|
|Alexa Fluor™ 750|
|50 mM sodium borate with 0.05% sodium azide|
|caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase|
|Store at 4°C in the dark.|
|Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok