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MAN1B1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550029

Catalog No. PA550029


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Description

Description

The antibody detects endogenous levels of total MAN1B1 protein.

Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309].
Specifications

Specifications

MAN1B1
Polyclonal
Unconjugated
MAN1B1
Liquid
MAN1B1
Synthesized peptide derived from internal of human MAN1B1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9UKM7, A2AJ15
Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, EC=3.2.1.113, ER alpha-1, 2-mannosidase
Rabbit
IgG
100 μL
-20°C
Primary
11253, 227619
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