MAP2K1 Monoclonal Antibody (OTI4F1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA505767

Catalog No. 50-167-6191

Description

MEK1 (mitogen activated protein kinase kinase, ERK kinase 1, microtubule-associated protein 2 kinase) is a dual specificity kinase and catalyses both a threonine and a tyrosine residue on MAP kinases ERK1 and ERK2. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in MEK1 can lead to cardiofaciocutaneous syndrome.

Specifications

• Antigen: MAP2K1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P31938, Q01986, Q02750
• Gene Symbols: MAP2K1
• Immunogen: Full length human recombit protein of human MAP2K1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4F1
• Conjugate: Unconjugated
• Gene: MAP2K1
• Gene Alias: CFC3, MAPKK1, MEK1, MKK1, PRKMK1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170851, 26395, 478347, 5604
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid