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MAPK7 Monoclonal Antibody (OTI4C1), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA502187

Encompass_Preferred

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Catalog No. 50-167-3265


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Description

Description

ERK5/MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5. It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver.
Specifications

Specifications

MAPK7
Monoclonal
0.59 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q13164
MAPK7
Full length human recombit protein of human MAPK7 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI4C1
Unconjugated
MAPK7
BMK1, ERK4, ERK5, PRKM7
Mouse
Affinity Chromatography
RUO
5598
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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