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MAPK7 Monoclonal Antibody (OTI4C1), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA502187
Description
ERK5/MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5. It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver.Specifications
MAPK7 | |
Monoclonal | |
0.59 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q13164 | |
MAPK7 | |
Full length human recombit protein of human MAPK7 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI4C1 | |
Unconjugated | |
MAPK7 | |
BMK1, ERK4, ERK5, PRKM7 | |
Mouse | |
Affinity Chromatography | |
RUO | |
5598 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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