Invitrogen™ MARVELD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520853

Catalog No. PIPA520853

Description

A suggested positive control is mouse heart tissue lysate. PA5-20853 can be used with blocking peptide PEP-0967.

MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Specifications

• Antigen: MARVELD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARVELD1
• Gene Alias: AI504298; bA548K23.8; GB14; MARVD1; MARVEL (membrane-associating) domain containing 1; MARVEL domain containing 1; MARVEL domain-containing protein 1; Marveld1; MRVLDC1; putative MARVEL domain-containing protein 1; RP11-548K23.8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 277010, 309375, 83742
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q7TQJ1, Q9BSK0
• Gene Symbols: MARVELD1
• Immunogen: A 16 amino acid peptide from near the amino terminus of human MARVELD1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG