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MASP Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS1723R

Catalog No. 50-198-4077


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Description

Description

MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
Specifications

Specifications

MASP
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MASP1
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
5648
MASP1
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P48740
3MC1; AW048060; C4/C2 activating component of Ra-reactive factor; CCPII; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; CRARF; CRARF1; mannan binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); Mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain; Mannose-binding lectin-associated serine protease 1; mannose-binding protein associated serine protease-1; Mannose-binding protein-associated serine protease; MAP1; MAp44; MASP; MASP1; MASP-1; Masp1/3; Masp3; PRSS5; Ra-reactive factor serine protease p100; RaRF; Serine protease 5; serine protease MASP1
KLH conjugated synthetic peptide derived from human MASP.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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