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MASP1 Mouse anti-Human, Clone: 4H2A9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA533362

Catalog No. PIMA533362


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Description

Description

Product is supplied at 1 mL (100 μL/mL).

MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
Specifications

Specifications

MASP1
Monoclonal
100 μg/mL
PBS with 0.1% BSA and 0.02% sodium azide
P48740
Man-binding lectin serine protease 1, Complement factor MASP-3, Mannose-binding lectin-associated serine protease 1, MASP-1, Ra-reactive factor serine protease p100, RaRF, Serine protease 5, Man-binding lectin serine protease 1 heavy chain, MASP1, CRARF, CRARF1, PRSS5
Mouse
IgG1
100 μg
4° C
Primary
5648
ELISA
4H2A9
Unconjugated
MASP1
liquid
MASP1
CCP-1 domain of MASP-1
Protein G
RUO
Antibody
Monoclonal
Human
SDS
Documents
Product Certifications
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