Tocris™ MaxiPost

Potassium channel modulator; exerts subtype-specific effects

Manufacturer: Tocris™ 4949/10

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Catalog No. 49-491-0

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For Research Use Only


    Product Type MaxiPost
    Inhibitors MaxiPost
    Purity >98
    Molecular Weight 359.7
    Quantity 10mg

    Potassium channel modulator. Acts as a positive modulator at neuronal Kv7 channels and calcium-activated K+ channels (BKCa) in HEK293 cells. Displays negative modulatory activity at Kv7.1 channels (Ki = 3.7µM) and GABAA receptors. Displays anxiolytic activity in vivo.

    • Chemical Name: (3S)-3-(5-Chloro-2-methoxyphenyl)-3-fluoro-1,3-dihydro-6-(trifluoromethyl)-2H-Indol-2-one
    • Formula: C16H10ClF4NO2
    • CAS Number: 187523-35-9
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

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