MCAM/CD146 Mouse anti-Human, Alexa Fluor™ 594, Clone: OJ79c, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234701AF594
DescriptionMCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen|
|CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin|
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)|
|Alexa Fluor 594|
|50 mM sodium borate with 0.05% sodium azide|
|Recombinant human MUC18 protein|
|Protein A or G purified|
|Store at 4°C in the dark.|
|The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.|
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