MCM7 Mouse anti-Human, PE/Atto594, Clone: MCM7/1469, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP259614PEATT594
DescriptionMCM7 Monoclonal antibody specifically detects MCM7 in Human samples. It is validated for Flow Cytometry.
|Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)|
|Protein A or G purified|
|Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers|
|PBS with 0.05% Sodium Azide|
|CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 126.96.36.199, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47|
|Store at 4°C in the dark. Do not freeze.|
|The specificity of this monoclonal antibody to human MCM7 was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.|
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