Tocris™ (±)-McN 5652

Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake in vitro

Manufacturer: Tocris™ 2148/10

 View more versions of this product

Catalog No. 21-481-0R

  Check Availability
Add to Cart

Disclaimers:

For Research Use Only


    Specifications

    Product Type (±)-McN 5652
    Inhibitors (±)-McN 5652
    Purity >95
    Molecular Weight 295.44
    Quantity 10mg

    Potent, high affinity serotonin re-uptake inhibitor; selective in vivo. Displays moderate selectivity over noradrenalin and dopamine re-uptake in vitro (Ki values are 0.68, 2.9 and 36.8nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Potently potentiates 5-HT-induced effects in vivo following oral administration. Biological activity resides predominantly in the (+)-enantiomer.

    • Chemical Name: (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline
    • Formula: C19H21NS
    • CAS Number: 96795-89-0
    • Solubility: Soluble to 50mM in 1eq. HCl and to 75mM in DMSO

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit