Invitrogen™ MCP-3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA546952

Catalog No. PIPA546952

Description

In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) MCP-1 is observed, approximately 15% cross-reactivity with rhEotaxin is observed, and less than 3% cross-reactivity with recombinant mouse Eotaxin, rhMARC, and rhMCP-2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.

Specifications

• Antigen: MCP-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCL7
• Gene Alias: C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20306
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q03366
• Gene Symbols: CCL7
• Immunogen: E. coli-derived recombinant mouse CCL7/MCP-3/MARC Gln24-Pro97.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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