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MeCP2 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen MeCP2
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3947 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39189
10 μL
Each for $135.30
N/A
50-199-3946 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39188
200 μL
Each for $534.00
N/A
Description

Description

MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Specifications

Specifications

Polyclonal
Primary
MeCP2
Unconjugated
SDS
Product Certifications
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