MECR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 149321AP
DescriptionThe mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q9BV79, Q9DCS3, Q9Z311|
|CGI 63, FASN2B, HsNrbf 1, MECR, NBRF1, NRBF 1, NRBF1|
|26922, 29470, 51102|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|MECR Fusion Protein Ag6738|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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