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MEF2C Mouse anti-Human, Clone: OTI2F2, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502552

Catalog No. 50-167-3601


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Description

Description

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Specifications

Specifications

MEF2C
Monoclonal
0.84 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q06413
C5DELq14.3, DEL5q14.3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4208
Immunohistochemistry (Paraffin), Western Blot
OTI2F2
Unconjugated
MEF2C
Liquid
MEF2C
Full length human recombit protein of human MEF2C produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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