Melanophilin Mouse anti-Human, Clone: OTI6E8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527001
DescriptionSlac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|2210418F23Rik, 5031433I09Rik, AW228792, D1Wsu84e, Slac-2a, l(1)-3Rk, l1Rk3, ln, exophilin-3, leaden protein, slaC2-a, slp homolog lacking C2 domains a, synaptotagmin-like protein 2a|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 295-600 of MLPH produced in E.coli|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok