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MEN1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 151591AP

Catalog No. 50-173-0029


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Description

Description

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.
Specifications

Specifications

MEN1
0.44 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O00255
MEAI, MEN1, Menin, multiple endocrine neoplasia I, SCG2
Rabbit
IgG
150 μL
-20°C
Primary
4221
Immunoprecipitation, Western Blot
Unconjugated
MEN1
Liquid
MEN1
MEN1 Fusion Protein Ag7253
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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