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Menin Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS1988R

Catalog No. 50-198-4384


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Description

Description

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.
Specifications

Specifications

Menin
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MEN1
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
4221
MEN1
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
O00255
AW045611; MEAI; MEN1; Menin; menin 1; multiple endocrine neoplasia 1; multiple endocrine neoplasia I; SCG2
KLH conjugated synthetic peptide derived from human Menin.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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