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  8. Methyl 4-bromocrotonate, tech. 85%, Thermo Scientific Chemicals

Methyl 4-bromocrotonate, tech. 85%, Thermo Scientific Chemicals

Catalog Number AAA1558230
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Quantity:
10 g
50 g
250 g
1117-71-1
C5H7BrO2
179.01
MFCD00000246,MFCD09998308
RWIKCBHOVNDESJ-NSCUHMNNSA-N
methyl 4-bromocrotonate, e-methyl 4-bromobut-2-enoate, 4-bromocrotonic acid methyl ester, methyl gamma-bromocrotonate, methyl bromocrotonate, methyl 4-bromo-2-butenoate, 2-butenoic acid, 4-bromo-, methyl ester, methyl 4-bromobut-2-enoate, methyl 2e-4-bromobut-2-enoate, crotonic acid, 4-bromo-, methyl ester
5369175
methyl (E)-4-bromobut-2-enoate
COC(=O)\C=C\CBr
1117-71-1
C5H7BrO2
179.01
MFCD00000246,MFCD09998308
RWIKCBHOVNDESJ-NSCUHMNNSA-N
methyl 4-bromocrotonate, e-methyl 4-bromobut-2-enoate, 4-bromocrotonic acid methyl ester, methyl gamma-bromocrotonate, methyl bromocrotonate, methyl 4-bromo-2-butenoate, 2-butenoic acid, 4-bromo-, methyl ester, methyl 4-bromobut-2-enoate, methyl 2e-4-bromobut-2-enoate, crotonic acid, 4-bromo-, methyl ester
5369175
methyl (E)-4-bromobut-2-enoate
COC(=O)\C=C\CBr

Description

It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

Solubility
Slightly soluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY
Density 1.524
Boiling Point 83°C to 85°C (13 mmHg)
Flash Point 91°C (195°F)
Refractive Index 1.501
Linear Formula BrCH2CH=CHCO2CH3
Quantity 250 g
UN Number UN1760
Beilstein 1745755
Solubility Information Slightly soluble in water.
Formula Weight 179.01
Percent Purity 85%
Grade Technical
Chemical Name or Material Methyl 4-bromocrotonate
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Safety and Handling

Hazard Category H227-H314-H335
Hazard Statement GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Precautionary Statement P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUIDS, N.O.S.
EINECSNumber 214-251-0
RTECSNumber GQ3120000
TSCA Yes
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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