METTL3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5121190

Catalog No. PIPA5121190

Description

Positive test controls include: 293T, HT-1080, NIH/3T3, Mouse testis, Mouse brain, Rat spleen. The target is usually found in the following locations: Nucleus speckle. Immunogen sequence: MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAM

METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Specifications

• Antigen: METTL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: METTL3
• Gene Alias: 2310024F18Rik; adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; fj82g07; hMETTL3; IME4; M6A; m6a methyltransferase; methyltransferase like 3; methyltransferase-like 3; methyltransferase-like protein 3; METTL3; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; MTA70; MT-A70; N6-adenosine-methyltransferase 70 kDa subunit; N6-adenosine-methyltransferase catalytic subunit; N6-adenosine-methyltransferase subunit METTL3; Spo8; Unknown (protein for MGC:77093); wu:fj82g07; zgc:77093
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361035, 56335, 56339
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q86U44, Q8C3P7
• Gene Symbols: METTL3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human METTL3 (NP_062826.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG