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MFN1 Mouse anti-Human, Clone: OTI4D11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526525

Catalog No. PIMA526525


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Description

Description

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Specifications

Specifications

MFN1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8IWA4
hfzo1, hfzo2, Mitofusin-1, Fzo homolog
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
55669
Immunohistochemistry (Paraffin), Western Blot
OTI4D11
Unconjugated
MFN1
Liquid
MFN1
Human recombit protein fragment corresponding to amino acids 209-469 of MFN1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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