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mGluR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 199551AP

Catalog No. 50-173-2621


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Description

Description

The antibody can recognize isoform1 and isoform2 of GRM1.

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
Specifications

Specifications

mGluR1
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97772, Q13255
GPRC1A, GRM1, GRM1A, mGlu1, mGluR1, MGLUR1A
Rabbit
IgG
150 μL
-20°C
Primary
14816, 2911
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
GRM1
Liquid
GRM1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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