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mGluR2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 199561AP

Catalog No. 50-173-2622


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Description

Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Specifications

Specifications

mGluR2
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P31421, Q14416, Q14BI2
GLUR2, GPRC1B, GRM2, mGlu2, mGluR2
Rabbit
IgG
150 μL
-20°C
Primary
108068, 24415, 2912
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
GRM2
Liquid
GRM2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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