mGluR4 Mouse anti-Human, Clone: OTI6D1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527293
DescriptionThe Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Metabotropic glutamate receptor 4, mGluR4, GPRC1D, MGLUR4, GRM4|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 126-407 of GRM4 produced in E.coli|
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